The Technion Autonomous Systems Program is a multi-departmental and multidisciplinary unit, founded in 2007 as the first of its kind in universities in Israel. Autonomous systems represent the next great step forward in the fusion of machines with sensors, computers, and communication capabilities. The objective is to develop intelligent systems that can interact dynamically with the complexities of the real world. Developments in artificial intelligence, machine learning, sensor technology, robotics and smart materials, among others, are the applied to development of theoretical and practical applications of autonomous systems.